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Research · Study

PCORI Study: IV Ketamine vs Esketamine for Treatment-Resistant Depression

This pragmatic clinical trial compares the effectiveness, safety, and patient experience of IV ketamine and intranasal esketamine in adults with treatment-resistant depression.

Content

Recruiting

Study overview

This pragmatic clinical trial compares the effectiveness, safety, and patient experience of IV ketamine and intranasal esketamine in adults with treatment-resistant depression.

Registry ID
NCT06713616
Phase / type
Interventional · Comparative Effectiveness
Ages
18+
Locations
Milford, CT

What participants should know

  • Compare IV ketamine with SPRAVATO® (esketamine)
  • Assess symptom change after eight treatments
  • Evaluate safety and tolerability

Study eligibility information

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